ARA-290 Overview
ARA-290, 16mg, lyophilized
Introduction
ARA-290 is a synthetic, non-erythropoietic peptide analog derived from the helix B surface of erythropoietin (EPO). This research compound represents an 11-amino acid sequence designed to interact with the innate repair receptor without engaging classical erythropoietin receptor pathways.
Scientific Background
ARA-290 was developed through structural analysis of erythropoietin's tissue-protective domains, specifically focusing on sequences that could potentially interact with the innate repair receptor (IRR) complex. Research into this compound emerged from investigations into EPO's non-hematopoietic properties, with scientists identifying specific regions of the EPO molecule that may be associated with tissue-protective activities independent of red blood cell production. The compound has been the subject of various preclinical and early-stage research investigations exploring cellular repair mechanisms and inflammatory response pathways.
ARA-290 Structural Information
- Amino Acid Sequence: Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser
- Molecular Formula: C₅₅H₈₆N₁₆O₁₉
- Molecular Weight: 1,257.35 g/mol
- Chemical Classification: Synthetic oligopeptide
- Structural Features: Contains pyroglutamic acid at N-terminus for enhanced stability
- Receptor Interaction: Designed to potentially interact with CD131/β-common receptor complex
- Modifications: Non-glycosylated linear peptide structure
Disclaimer Section
This information is provided for educational and research purposes only. ARA-290 is a research compound not approved for human use. These statements have not been evaluated by the FDA or any regulatory authority. This compound is not intended to diagnose, treat, cure, or prevent any disease or medical condition.
Research use of this compound should only be conducted by qualified professionals in appropriate laboratory settings with proper institutional oversight and in compliance with all applicable regulations. Not for human consumption or clinical use.
The information presented reflects current scientific literature available for educational review and does not constitute medical advice or therapeutic recommendations.